New positive inotropic agents in the treatment of left ventricular dysfunction.
نویسندگان
چکیده
Three major classes of inotropic agents have been clinically evaluated in patients with left ventricular dysfunction: a) agents that increase the intracellular concentration of cyclic adenosine monophosphate by stimulating the beta-adrenergic receptor or inhibiting phosphodiesterase; b) drugs that increase the intracellular sodium concentration; c) the new calcium-sensitizing drugs. This review will focus on the newest drug for each of the above-mentioned classes of inotropic agents. Moreover, we present a new protocol which provides the use of levosimendan in patients with post-ischemic left ventricular dysfunction.
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ورودعنوان ژورنال:
- Italian heart journal : official journal of the Italian Federation of Cardiology
دوره 5 Suppl 6 شماره
صفحات -
تاریخ انتشار 2004